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Pierre Verrelle Selected Research

Proteins (Proteins, Gene)

1/2021Widespread overexpression from the four DNA hypermethylated HOX clusters in aggressive (IDHwt) glioma is associated with H3K27me3 depletion and alternative promoter usage.
10/2019Transcriptional alterations in glioma result primarily from DNA methylation-independent mechanisms.
1/2019Combining the DNA Repair Inhibitor Dbait With Radiotherapy for the Treatment of High Grade Glioma: Efficacy and Protein Biomarkers of Resistance in Preclinical Models.
2/2017SETMAR isoforms in glioblastoma: A matter of protein stability.
1/2017A 13-gene expression-based radioresistance score highlights the heterogeneity in the response to radiation therapy across HPV-negative HNSCC molecular subtypes.
6/2013αvβ3 Integrin and Fibroblast growth factor receptor 1 (FGFR1): Prognostic factors in a phase I-II clinical trial associating continuous administration of Tipifarnib with radiotherapy for patients with newly diagnosed glioblastoma.

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Pierre Verrelle Research Topics

Disease

31Neoplasms (Cancer)
06/2022 - 05/2002
16Glioma (Gliomas)
04/2022 - 04/2007
15Glioblastoma (Glioblastoma Multiforme)
01/2022 - 01/2002
7Squamous Cell Carcinoma of Head and Neck
08/2021 - 11/2003
6Neoplasm Metastasis (Metastasis)
01/2022 - 01/2008
4Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
09/2022 - 11/2015
4Breast Neoplasms (Breast Cancer)
02/2010 - 05/2002
3Brain Neoplasms (Brain Tumor)
09/2022 - 10/2019
2Head and Neck Neoplasms (Head and Neck Cancer)
08/2021 - 06/2006
2Melanoma (Melanoma, Malignant)
03/2016 - 10/2014
2Adenocarcinoma
01/2014 - 11/2003
2Prostatic Neoplasms (Prostate Cancer)
01/2014 - 07/2007
2Carcinoma (Carcinomatosis)
11/2007 - 11/2002
1Inflammation (Inflammations)
04/2022
1Fibrosis (Cirrhosis)
12/2020
1Urinary Bladder Neoplasms (Bladder Cancer)
12/2020
1Astrocytoma (Pilocytic Astrocytoma)
11/2019
1Pulmonary Embolism
02/2017
1Sudden Death
02/2017
1Arthrogryposis renal dysfunction cholestasis syndrome
04/2016
1Hepatocellular Carcinoma (Hepatoma)
03/2016
1Colorectal Neoplasms (Colorectal Cancer)
03/2016
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
03/2016
1Lung Neoplasms (Lung Cancer)
04/2013
1Oligodendroglioma
01/2013
1Chromosome Aberrations (Chromosome Abnormalities)
10/2011
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
04/2011
1Sialorrhea
04/2011
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
12/2009
1Medulloblastoma
09/2007

Drug/Important Bio-Agent (IBA)

6Proteins (Proteins, Gene)FDA Link
01/2021 - 06/2013
5DNA (Deoxyribonucleic Acid)IBA
01/2021 - 03/2011
4Biomarkers (Surrogate Marker)IBA
01/2022 - 07/2017
4Messenger RNA (mRNA)IBA
02/2017 - 12/2009
3Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
04/2022 - 10/2019
3Telomerase (Telomerase Reverse Transcriptase)IBA
11/2019 - 10/2011
3Phosphotransferases (Kinase)IBA
06/2014 - 01/2014
3Temozolomide (Temodar)FDA LinkGeneric
08/2012 - 04/2007
2Serine (L-Serine)FDA Link
10/2017 - 01/2016
2Tyrosine (L-Tyrosine)FDA Link
10/2017 - 01/2016
2Gefitinib (Iressa)FDA Link
02/2017 - 11/2003
2Protein Isoforms (Isoforms)IBA
02/2017 - 04/2014
2Pharmaceutical PreparationsIBA
01/2017 - 09/2007
2Biological ProductsIBA
01/2017 - 01/2012
2Fluorouracil (Carac)FDA LinkGeneric
12/2015 - 07/2011
2Radiation-Sensitizing AgentsIBA
11/2015 - 10/2011
2LigandsIBA
11/2015 - 10/2011
2Interleukin-6 (Interleukin 6)IBA
07/2007 - 01/2002
1Long Noncoding RNAIBA
04/2022
1Transcription Factors (Transcription Factor)IBA
04/2022
1Retroelements (Retrotransposon)IBA
01/2022
1mesoglycanIBA
12/2020
1STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
10/2017
1ChromatinIBA
02/2017
1O(6)-Methylguanine-DNA MethyltransferaseIBA
02/2016
1Cisplatin (Platino)FDA LinkGeneric
12/2015
1Vinorelbine (Navelbine)FDA LinkGeneric
12/2015
1PlatinumIBA
11/2015
11,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA
10/2014
1NucleophosminIBA
01/2014
1Epidermal Growth Factor (EGF)IBA
01/2014
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2014
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
01/2014
1tipifarnib (R115777)IBA
06/2013
1Type 1 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 1)IBA
06/2013
1Farnesyltranstransferase (Farnesyltransferase)IBA
06/2013
1IntegrinsIBA
06/2013
1Hydroxyurea (Hydrea)FDA LinkGeneric
07/2011
1Methotrexate (Mexate)FDA LinkGeneric
07/2011
15233705 compoundIBA
05/2010
1Dihydrotachysterol (AT 10)IBA
02/2010
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2009
1L 35 (L35)IBA
04/2008
1Contrast MediaIBA
04/2008
1Cytotoxins (Cytolysins)IBA
09/2007
1Carmustine (FIVB)FDA Link
04/2007
1ErbB Receptors (EGF Receptor)IBA
11/2003
1Cetuximab (Erbitux)FDA Link
11/2003
1Trastuzumab (Herceptin)FDA Link
11/2003
1Tyrosine Kinase InhibitorsIBA
11/2003
1QuinazolinesIBA
11/2003
1AntibodiesIBA
11/2003
1Canertinib (CI 1033)IBA
11/2003
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
11/2002
1TransferasesIBA
11/2002

Therapy/Procedure

26Radiotherapy
09/2022 - 11/2003
6Drug Therapy (Chemotherapy)
02/2017 - 09/2007
5Therapeutics
08/2021 - 04/2008
3Chemoradiotherapy
01/2017 - 11/2007
3Neoadjuvant Therapy
02/2010 - 05/2002
2Re-Irradiation
06/2022 - 07/2011
2Intensity-Modulated Radiotherapy (Radiotherapy, Intensity Modulated)
01/2021 - 04/2016
1Cystectomy
12/2020
1Pneumonectomy (Lung Volume Reduction)
04/2013
1Particle Accelerators
01/2013
1Lymph Node Excision (Lymph Node Dissection)
02/2010
1Intravenous Injections
04/2008
1Cryotherapy (Therapy, Cold)
01/2008
1Transplantation
04/2007
1Induction Chemotherapy
11/2002